This article discusses the role of the prefrontal cortex in mediating passive coping behaviors in response to chronic stress and the effects of fast-acting antidepressants.
Neurons responsible for boosting the intensity of breathing when organs need more oxygen have been identified, unveiling a new target for treatments seeking to restore breathing after a spinal cord injury.
Emerging research hints at a powerful combination; AI and gene therapy poised to enhance brain treatments and offer solutions to some of the most challenging mental health disorders. Much like a recipe book for the mind, this approach adds a splash of engineering to physiological healing.
Researchers have developed organoid models to identify potential new treatment targets for Alzheimer's disease, enhancing the prospective efficacy of therapies.
A fading sense of smell may be one of the earliest warning signs of Alzheimer’s disease, with researchers discovering that microglia mistakenly remove nerve fibers crucial for processing odors, linking this phenomenon to the disease.
This clinical trial evaluates the effectiveness of MDMA-assisted therapy among veterans suffering from PTSD and comorbid alcohol use disorder, aiming to improve treatment outcomes.
This paper offers a multi-agent framework involving large language models (LLMs) aimed at improving therapy and mental disorder diagnosis, emphasizing trustworthiness and explainability.
A phase 1/2 trial of dual-vector rAAVrh8 gene therapy for GM2 gangliosidosis, administered by bilateral intrathalamic, cisterna magna and intrathecal delivery found a dose-dependent biochemical correction of the disease.
In cohort B of the phase 2 SWOG S1512 trial, pembrolizumab monotherapy in patients with unresectable desmoplastic melanoma elicited a complete response rate of 37% and an objective response rate of 89%, supporting a new treatment option for this tumor type.
A randomized controlled trial found no difference in paranoid ideations between virtual reality-based and gold-standard cognitive behavioral therapy for patients with schizophrenia spectrum disorders, in contrast to previous trials using wait-list or passive controls.
Scientists at UC San Diego have discovered a small but powerful section of DNA, called HAR123, that could help explain what makes the human brain so unique. Instead of being a gene, HAR123 acts like a switch controlling the development of neural processes.
Researchers show that fragments of microbial DNA circulating in blood can distinguish between primary liver cancer and colorectal cancer that has metastasized to the liver.
This clinical trial investigates the implementation of a therapy designed for patients suffering from Complex Trauma in French-speaking environments, focusing on outcomes related to PTSD and related disorders.
This study investigates the alterations in calcium dynamics in reactive astrocytes associated with amyloid pathology in a mouse model of Alzheimer's disease, revealing potential mechanisms underlying neurovascular dysfunction.
A large language model designed for health monitoring provides personalized sleep and fitness predictions, insights and advice.
A new study uncovers a pancreas–hippocampus feedback loop that may help explain mood swings in bipolar disorder. Using patient-derived pancreatic islets, researchers found reduced insulin secretion linked to elevated RORβ, a bipolar risk gene.