This study investigates the regulation of NMDA glutamate receptor 2B and mitochondrial calcium uniporter by phospho-CREB in the ventrolateral periaqueductal gray, focusing on their role in chronic morphine withdrawal in male rats.
The study explains how the ventral tegmental area in the brain not only signals when rewards will happen but predicts the exact timing of these rewards.
The article discusses a revised preprint that explores how reversal learning is processed within the prefrontal cortex using recurrent neural networks, demonstrating relevant dynamics and highlights.
This study reveals how the brain anticipates words during naturalistic speech, with evidence indicating that higher predictability decreases N400 amplitudes in EEG recordings. Such findings enhance the understanding of predictive processing in language comprehensions and suggest implications for the development of neuroscience-inspired AI.
Recent voxel-wise multimodal brain encoding studies demonstrated that multimodal large language models (MLLMs) exhibit significant brain alignment compared to unimodal models. Instruction-tuned MLLMs show stronger alignment with brain activity during naturalistic tasks, outperforming earlier models in differentiation of multimodal functional processing in the brain.
A 60-year-old anesthetic is rewiring traumatized brains in hours, not months. Could this change everything for millions suffering from trauma?
This paper presents a model of second-person neuroscience through active inference, enabling investigation of social cognition dynamics during interactions. The proposed geometric hyperscanning method operationalizes this by tracking topological changes in inter-brain networks, emphasizing the role of affect in social interactions.
This article explores the role of NINJ1 in maintaining plasma membrane integrity under mechanical strain, with implications for understanding cellular responses to physical stress.
Research indicates that late-life mood disorders such as depression and bipolar disorder may serve as early indicators of Alzheimer's disease. Advanced brain imaging and postmortem analysis show that many patients with these mood disorders exhibit tau accumulation, a key marker of neurodegeneration.
The article explores the function of hypothalamic CRH neurons in modulating the effects of stress on memory processes and sleep patterns.
This revised preprint investigates the opposing regulatory mechanisms of TNF responses mediated by IFN-γ and the PGE2-cAMP axis in macrophages associated with rheumatoid arthritis, providing insights into therapeutic implications.
The article argues against common criticisms of machine learning in economics, asserting that new methods are improving causal inference.
This study presents a low-rank neural network modeling approach to understanding how selection mechanisms work in context-dependent computations.
Autism is associated with inflexibility of brain dynamics. Watanabe and Yamasue show that TMS over the right superior parietal lobule while the brain is ‘stuck’ in a certain state reduces this rigidity and relieves various autistic traits.
This study investigates the factors influencing reinforcement motor learning in children, emphasizing age as a key predictor of learning effectiveness.
The article discusses the findings related to the activation of sleep rhythms across the human brain, contributing to the understanding of its implications for sleep sciences.