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Early life adversity may fundamentally rewire global brain dynamics

by PsyPost

Research shows that experiences of early life adversity can lead to significant changes in how brain networks operate, with implications for understanding mental health.

PsyPost
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EdgeSSVEP: A Fully Embedded SSVEP BCI Platform for Low-Power Real-Time Applications

by Manh-Dat Nguyen et al.

This paper presents EdgeSSVEP, a microcontroller-based Steady-State Visually Evoked Potential (SSVEP) BCI platform that performs real-time EEG acquisition and on-device classification while operating at low power (222 mW). The study achieved 99.17% classification accuracy over 10 participants with various stimulus frequencies.

Neural Digital Twins: Toward Next-Generation Brain-Computer Interfaces

by Mohammad Mahdi Habibi Bina et al.

This article introduces the concept of Neural Digital Twin (NDT) as a solution to the limitations of current neural interfaces. NDT involves creating a dynamic computational model of the brain-BCI system that learns from real-time neural data, optimizing control commands, and adapting decoding algorithms.

The Goo That Binds Us: How Field Resonance Solves Neuroscience's Binding and Criticality Problems

by Tam Hunt

This article presents a hypothesis on how field resonance may address binding and criticality issues faced in neuroscience.

Frontiers in Computational Neuroscience
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Oxytocin reduces anger bias, harm-intention recognition, and self-focus in behavioral variant frontotemporal dementia: A randomized double-blind placebo-controlled crossover trial

by Valentina Colonnello

This study examines the effects of oxytocin on emotional bias and recognition in patients with behavioral variant Frontotemporal Dementia (bvFTD), showing that oxytocin can diminish anger bias and enhance recognition of harm-intentions.

Frontiers in Aging Neuroscience
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gPC-based robustness analysis of neural systems through probabilistic recurrence metrics

by Uros Sutulovic

This paper introduces a computational framework for probabilistic robustness analysis of dynamical systems in neuroscience, successfully applying it to models like the Hindmarsh-Rose and Jansen-Rit models. The method assesses the preservation of neural signaling regimes under uncertainty by employing generalized polynomial chaos and new metrics.

arXiv Neurons and Cognition
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P75NTR blockading inhibits Trem2+ M1 phenotype microglia activation and myelin damage following mild traumatic brain injury

by Xu Li et al.

This study investigates the effects of P75NTR blockading on M1 phenotype microglia activation and myelin damage in a model of mild traumatic brain injury.

Frontiers in Neuroscience
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Transformers self-organize like newborn visual systems when trained in prenatal worlds

by Lalit Pandey

The paper investigates whether transformers trained on prenatal visual input develop structures similar to newborn visual systems. Findings show that, under such training, transformers exhibit edge detection and shape sensitivity, suggesting common learning principles between biological and artificial systems.

arXiv Neurons and Cognition
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Early Screen Time Linked to Long-Term Brain Changes, Teen Anxiety

by Neuroscience News

A recent investigation finds a correlation between early exposure to screens and long-term alterations in brain structure, which may contribute to increased anxiety in teenagers. This research underscores the effects of digital media on adolescent mental health.

Neuroscience News
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Refreshing the Brain’s Immune Cells Could Treat a Host of Diseases

by Shelly Fan

Introducing a dashing knight in therapeutic armor: the revivification of brain's immune cells as a novel treatment. This innovation breathes hope into treating entwined neurological ailments. Quite literally, a breath of fresh cell! Original source is Singularity Hub.

Singularity Hub
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Direct MRI of Collagen

by Jason Daniel van Schoor et al.

This preprint presents a novel method for directly imaging collagen using MRI techniques, which could have significant implications for biomedical imaging and tissue assessment.

Synaptic potentiation requires PARP1 activation: prevailing concepts are revisited

by Malka Cohen-Armon et al.

This article discusses the role of PARP1 activation in synaptic potentiation, challenging traditional understanding and suggesting new pathways for research in neurobiology.

Nature Molecular Psychiatry
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Immune Signal Ratio May Predict Progressive Multiple Sclerosis

by Neuroscience News

A new study uncovers a specific ratio of immune signals that could predict the likelihood of developing progressive multiple sclerosis. This finding provides insight into potential biomarkers for disease progression.

Neuroscience News
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Spatial transcriptomics of the developing mouse brain immune landscape reveals effects of maternal immune activation and microbiome depletion

by Bharti Kukreja et al.

The research utilizes spatial transcriptomics to map immune gene expression in the developing mouse brain, identifying critical sex-specific changes due to maternal gut and immune changes.

Nature Neuroscience
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Functional heterogeneity in non-suicidal self-injury across psychiatric disorders: neural and psychosocial correlates

by Mingzhu Li et al.

This article discusses the neural and psychosocial correlates associated with different forms of non-suicidal self-injury across various psychiatric disorders, highlighting the functional heterogeneity observed.

Translational Psychiatry
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CRISPR knockout screens reveal genes and pathways essential for neuronal differentiation and implicate PEDS1 in neurodevelopment

by Alana Amelan et al.

The study conducted a CRISPR screen to identify genes essential for neural differentiation, linking findings with mouse neuroanatomy and identifying a new PEDS1-related neurodevelopmental disorder.

Nature Neuroscience
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