This article investigates the comparative effectiveness of 10 Hz repetitive transcranial magnetic stimulation (rTMS) and intermittent theta burst stimulation (iTBS) on the brain connectivity of individuals with major depressive disorder (MDD) in a randomized sham-controlled study.
This study utilizes multi-omics approaches to reveal new synapse-associated targets relevant to Alzheimer's disease, potentially providing insights into its pathology and offering avenues for future therapeutic strategies.
This research article presents findings from single-cell transcriptomic analyses identifying Sox6 positive interneurons in the prefrontal cortex of female mice, linking them to vulnerability to chronic social stress.
This study explores the use of H1 coil Transcranial Magnetic Stimulation (TMS) targeting depression circuitry, presenting findings from a retrospective analysis of circuit mapping that suggest its effectiveness.
This article examines the relationship between circulating endocannabinoids and anxiety in children and adolescents, along with the effects of selective serotonin reuptake inhibitors (SSRIs).
Fascinating study on how deleting a gene called PTEN in mice messes with their fear wiring, leading to anxiety-like behavior. Insights here could possibly help us decode similar anxiety traits in humans. Mice, however, were unreachable for comment.
This study investigates the age-related changes in locus coeruleus activity and its connectivity with the prefrontal cortex during ambiguity processing, providing insights into the neurobiological underpinnings of decision-making across the lifespan.
This survey reviews various human behavior modalities utilized for automatic depression assessment (ADA) using machine learning. It highlights existing challenges, compares different approaches, and summarizes multi-modal depression-related behaviors, emphasizing the need for comprehensive methodologies in this field.
The study examines how positive early life experiences can mitigate the risk of suicidal thoughts among individuals with trauma backgrounds, suggesting pathways for preventative measures.
A new meta-analysis reveals that Electroconvulsive Therapy (ECT) reduces suicide risk by 34% and all-cause mortality by 30% in individuals with severe depression. The study, which pooled data from 26 high-quality studies, compared nearly 18,000 patients treated with ECT to over 25,000 who received standard care. ECT also modestly reduced suicidal thoughts, showing broader health benefits beyond mental health.
Scientists have uncovered a surprising sugar-related mechanism inside brain cells that could transform how we fight Alzheimer’s and other dementias. It turns out neurons don’t just store sugar; they also use it to protect themselves from harmful energy fluctuations.
This randomized trial evaluates the effectiveness of EEG-based neurofeedback in enhancing emotion regulation among adults with Major Depressive Disorder.
Researchers have developed a retinal prosthesis made of tellurium nanowires that restores partial vision in blind mice and enables near-infrared vision in primates. The implant, woven into a lattice of light-sensitive nanowires, converts both visible and near-infrared light into electrical signals for the brain.
This article discusses the emerging role of artificial intelligence in the biomedical field, specifically focusing on AI agents that analyze and interpret biological data.
This study examines the efficacy of using music as an intervention to mitigate anxiety levels in individuals undergoing intrauterine device application. The focus is on the psychological impact of music during medical procedures.
A clinical trial aimed to determine whether imaging-targeted or scalp-targeted Accelerated TMS is more effective in treating Major Depressive Disorder (MDD).