Elata News

Inference technique for the synaptic conductances in rhythmically active networks and application to respiratory central pattern generation circuits

by Anke Borgmann et al.

Ah, the delightful ballet of synaptic interactions in rhythmic neural circuits, such as those motor behaviors that keep us ticking. This paper unveils the role of excitatory and inhibitory interneurons in decoding those delightful interactions, vital for decrypting circuit puzzles, particularly in those pesky central pattern generation circuits.

Elifesciences.org

Beckley’s 5-MeO-DMT Shows Rapid, Durable Antidepressant Effects in Phase 2b Study

by Psychedelic Alpha

Beckley Psytech shares positive topline data from its Phase 2b study of intranasal 5-MeO-DMT (BPL-003) in treatment-resistant depression (TRD), indicating rapid antidepressant effects and a favorable safety profile.

Psychedelic Alpha

Child-Parent Psychotherapy After the 2023 Kahramanmaraş Earthquake

by Clinical Trials

A clinical study focused on the effectiveness of child-parent psychotherapy in addressing PTSD following significant trauma caused by the 2023 Kahramanmaraş earthquake.

Clinical Trials

The Somatic Mosaicism across Human Tissues Network

by Tim H. H. Coorens et al.

The Somatic Mosaicism across Human Tissues Network aims to create a reference catalogue of somatic mosaicism across different tissues and cells within individuals.

Nature

A foundation model to predict and capture human cognition

by Marcel Binz et al.

A computational model called Centaur, developed by fine-tuning a language model on a huge dataset called Psych-101, can predict and simulate human nature in experiments expressible in natural language, even in previously unseen situations.

Nature Psychology

Is cardiac autonomic control affected in major depressive disorder? A systematic review of heart rate variability studies

by Federica Goffi et al.

This systematic review investigates the impact of major depressive disorder on cardiac autonomic control, focusing on heart rate variability as a key physiological measure. It aims to summarize findings from various studies to assess the implications for understanding depression-related cardiovascular risks.

Nature Translational Psychiatry

Age Sensitive Hippocampal Functional Connectivity: New Insights from 3D CNNs and Saliency Mapping

by Yifei Sun et al.

This study explores the functional connectivity changes in the hippocampus related to aging using a deep learning framework that predicts brain age from functional connectivity data. The findings reveal distinct mappings of anterior and posterior hippocampal connectivity that are crucial for understanding hippocampal aging mechanisms.

arXiv

A neuromorphic model of active vision shows how spatiotemporal encoding in lobula neurons can aid pattern recognition in bees

by HaDi MaBouDi et al.

Active vision dynamically refines spatiotemporal neural representations, optimising visual processing through scanning behaviour and non-associative learning, providing insights into efficient sensory encoding in dynamic environments.

eLife

First human genome from ancient Egypt sequenced from 4,800-year-old teeth

by Ewen Callaway

Forty years after the first effort to extract mummy DNA, researchers have finally generated a full genome sequence from an ancient Egyptian.

Nature

Brain Stimulation Reverses Synaptic Damage in Alzheimer’s

by Neuroscience News

New research shows that low-intensity repetitive transcranial magnetic stimulation (rTMS) can restore key synaptic structures in mouse models of Alzheimer’s disease. The study found that axonal boutons—sites where neurons form connections—had reduced turnover in Alzheimer’s mice, indicating impaired brain plasticity.

Neuroscience News

AI Facial Analysis Detects PTSD

by Neuroscience News

Diagnosing PTSD in children is often hindered by limited communication and emotional awareness, but new research is using AI to bridge that gap. By analyzing facial movements during interviews, researchers created a privacy-preserving tool that can identify PTSD-related expression patterns. Their system does not use raw video but instead tracks non-identifying facial cues such as eye gaze and mouth movement.

Neuroscience News

A Midlife MRI That Spots Rapid Aging and Signals Disease Long Before Symptoms

by Science Daily

A new brain scan tool shows how quickly your body and mind are aging. It can spot early signs of diseases like dementia, long before symptoms begin.

Science Daily

Targeting depression circuitry with H1 coil Transcranial Magnetic Stimulation: a retrospective circuit mapping study

by Samantha Baldi et al.

This article explores the use of H1 coil Transcranial Magnetic Stimulation to target circuitry associated with depression, analyzing its efficacy through a retrospective mapping study.

Nature Neuropsychopharmacology

Efficacy of a Personalized, Response-based Transdiagnostic Intervention for Emotional Disorders Delivered Via the Internet: A Protocol for an Adaptive Trial

by ClinicalTrials.gov

This clinical study protocol details a personalized and response-based intervention for emotional disorders aimed to be delivered via the internet. The study targets various emotional disorders, including depression.

ClinicalTrials.gov

Clinical Effect and Mechanism Study of Five Elements Music Therapy(FEMT) on Depression Disorder

by ClinicalTrials.gov

This study aims to explore the clinical effects and underlying mechanisms of Five Elements Music Therapy on individuals suffering from Depression Disorder.

ClinicalTrials.gov

Combining rTMS & Aerobic Exercise to Treat Depression and Improve Post-Stroke Walking

by ClinicalTrials.gov

This study will explore the combined efficacy of repetitive Transcranial Magnetic Stimulation (rTMS) and aerobic exercise in treating depression and enhancing walking abilities post-stroke.

ClinicalTrials.gov